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KMID : 1189420170300030001
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2017 Volume.30 No. 3 p.1 ~ p.19
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Efficacy of Herbal Medicines for the Treatment of Psoriasis : Systematic Review and Meta-analysis
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Ryu Deok-Hyun
Ryu Deok-Seon
Roh Seok-Sun
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Abstract
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Objectives : This study aimed to validate the effect of herbal medicine intervention to relieve the symptoms of psoriasis using systematic review and meta-analysis and provide the newest reason of effectiveness of Korean medicine to psoriasis.
Methods : Data were collected through electronic database including Pubmed, Cochrane CENTRAL, NDSL OASIS, Koreantk. Two experts assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool after searching, reviewing and selecting papers. Data were analyzed using Review Manager(RevMan) 5.3 and Comprehensive Meta Analysis 2.0.
Results : Total number of selected trials was 16 randomized controlled trials. This study evaluated the risk of bias and effectiveness of herbal medicine to psoriasis. There were high frequency uncertain in selection bias, performance bias and detection bias. In this meta-analysis, Korean medicine treatment was more effective than western medicine (ES:0.507, 95%CI:0.147-0.867) and placebo (ES:0.955, 95%CI:0.598-1.312).
Conclusions : Herbal medicine intervention can be an effective for treatment in psoriasis. But enhancing levels of evidence, we must try to accumulate clinical researches of herbal medicine to psoriasis in Korea.
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KEYWORD
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Psoriasis , Herbal medicine , Systematic review , Meta-analysis
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